Self-establishing communities enable cooperative metabolite exchange in a eukaryote

Self-establishing communities enable cooperative metabolite exchange in a eukaryote

Metabolite exchange among co-growing cells is frequent by nature, however, is not necessarily occurring at growth-relevant quantities indicative of non-cell-autonomous metabolic function. Complementary auxotrophs of Saccharomyces cerevisiae amino acid and nucleotide metabolism regularly fail to comp...

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Bibliographic Details
Main Authors: Kate Campbell, Jakob Vowinckel, Michael Mülleder, Silke Malmsheimer, Nicola Lawrence, Enrica Calvani, Leonor Miller-Fleming, Mohammad T Alam, Stefan Christen, Markus A Keller, Markus Ralser
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
metabolism
cooperativity
cellular heterogeneity
Online Access:https://elifesciences.org/articles/09943

Internet

https://elifesciences.org/articles/09943

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