Functional and molecular characterization of hyposensitive underactive bladder tissue and urine in streptozotocin-induced diabetic rat.

The functional and molecular alterations of nerve growth factor (NGF) and Prostaglandin E2 (PGE2) and its receptors were studied in bladder and urine in streptozotocin (STZ)-induced diabetic rats.Diabetes mellitus was induced with a single dose of 45 mg/kg STZ Intraperitoneally (i.p) in female Sprag...

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Bibliographic Details
Main Authors: Jayabalan Nirmal, Pradeep Tyagi, Yao-Chi Chuang, Wei-Chia Lee, Naoki Yoshimura, Chao-Cheng Huang, Bharathi Rajaganapathy, Michael B Chancellor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4106869?pdf=render