Multiscale modeling of red blood cell mechanics and blood flow in malaria.

Red blood cells (RBCs) infected by a Plasmodium parasite in malaria may lose their membrane deformability with a relative membrane stiffening more than ten-fold in comparison with healthy RBCs leading to potential capillary occlusions. Moreover, infected RBCs are able to adhere to other healthy and...

Full description

Bibliographic Details
Main Authors: Dmitry A Fedosov, Huan Lei, Bruce Caswell, Subra Suresh, George E Karniadakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3228770?pdf=render