Accumulation and Toxicity of Superparamagnetic Iron Oxide Nanoparticles in Cells and Experimental Animals

Accumulation and Toxicity of Superparamagnetic Iron Oxide Nanoparticles in Cells and Experimental Animals

The uptake and distribution of negatively charged superparamagnetic iron oxide (Fe3O4) nanoparticles (SPIONs) in mouse embryonic fibroblasts NIH3T3, and magnetic resonance imaging (MRI) signal influenced by SPIONs injected into experimental animals, were visualized and investigated. Cellular uptake...

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Bibliographic Details
Main Authors: Greta Jarockyte, Egle Daugelaite, Marius Stasys, Urte Statkute, Vilius Poderys, Ting-Chen Tseng, Shan-Hui Hsu, Vitalijus Karabanovas, Ricardas Rotomskis
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
magnetic nanoparticles
SPIONs
iron oxide
cellular uptake
MRI-optical dual imaging
optical biopsy of tissues cells
multifunctional cancer diagnostics
Online Access:http://www.mdpi.com/1422-0067/17/8/1193

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http://www.mdpi.com/1422-0067/17/8/1193

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