Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933

Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933

Purpose: NRG Oncology's RTOG 0933 demonstrated benefits to memory preservation after hippocampal avoidant whole-brain radiation therapy (HA-WBRT), the avoidance of radiation dose to the hippocampus (using intensity modulated radiation planning and delivery techniques) during WBRT, supporting th...

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Main Authors: Joseph A. Bovi, MD, Stephanie L. Pugh, PhD, David Sabsevitz, PhD, Clifford G. Robinson, MD, Eric Paulson, PhD, Minesh P. Mehta, MD, Vinai Gondi, MD, Vijayananda Kundapur, MD, Mark S. Shahin, MD, Samuel T. Chao, MD, Mitch Machtay, MD, Albert S. DeNittis, MD, Nadia N. Laack, MD, Jeffrey N. Greenspoon, MD, Kathleen N. Moore, MD, Jiayi Huang, MD, Michael M. Dominello, DO, Lisa A. Kachnic, MD
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109419300909

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http://www.sciencedirect.com/science/article/pii/S2452109419300909

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