Intrathecal morphine administration reduces postoperative pain and peripheral endocannabinoid levels in total knee arthroplasty patients: a randomized clinical trial

Intrathecal morphine administration reduces postoperative pain and peripheral endocannabinoid levels in total knee arthroplasty patients: a randomized clinical trial

Abstract Background The primary goal of this study was to determine whether administration of intrathecal morphine reduces postoperative pain. The secondary goal was to determine the effect of intrathecal morphine upon circulating levels of the weakly analgesic endocannabinoids, anandamide (AEA) and...

Full description

Bibliographic Details
Main Authors: Martin Kaczocha, Syed Azim, James Nicholson, Mario J. Rebecchi, Yong Lu, Tian Feng, Jamie L. Romeiser, Ruth Reinsel, Sabeen Rizwan, Shivam Shodhan, Nora D. Volkow, Helene Benveniste
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Anesthesiology
Subjects:
Endocannabinoid
Pain
Total knee arthroplasty
Anandamide
Morphine
Online Access:http://link.springer.com/article/10.1186/s12871-018-0489-5

Internet

http://link.springer.com/article/10.1186/s12871-018-0489-5

Similar Items