Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia.

Infection with the human liver fluke Opisthorchis viverrini induces cancer of the bile ducts, cholangiocarcinoma (CCA). Injury from feeding activities of this parasite within the human biliary tree causes extensive lesions, wounds that undergo protracted cycles of healing, and re-injury over years o...

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Bibliographic Details
Main Authors: Michael J Smout, Javier Sotillo, Thewarach Laha, Atiroch Papatpremsiri, Gabriel Rinaldi, Rafael N Pimenta, Lai Yue Chan, Michael S Johnson, Lynne Turnbull, Cynthia B Whitchurch, Paul R Giacomin, Corey S Moran, Jonathan Golledge, Norelle Daly, Banchob Sripa, Jason P Mulvenna, Paul J Brindley, Alex Loukas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005209