Temporal changes in glutaredoxin 1 and protein s-glutathionylation in allergic airway inflammation.

Asthma is a chronic inflammatory disorder of the airways, involving oxidative stress. Upon oxidative stress, glutathione covalently binds to protein thiols to protect them against irreversible oxidation. This posttranslational modification, known as protein S-glutathionylation, can be reversed by gl...

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Bibliographic Details
Main Authors: Kanako Maki, Katsura Nagai, Masaru Suzuki, Takashi Inomata, Takayuki Yoshida, Masaharu Nishimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395207?pdf=render