Quetiapine Attenuates Schizophrenia-Like Behaviors and Demyelination in a MK-801–Induced Mouse Model of Schizophrenia

Quetiapine Attenuates Schizophrenia-Like Behaviors and Demyelination in a MK-801–Induced Mouse Model of Schizophrenia

Brain demyelination is possibly one of the main pathological factors involved in schizophrenia, and targeting on myelination may be a useful strategy for schizophrenia treatment. Quetiapine, a widely used atypical antipsychotic drug for schizophrenia treatment, has been reported to have neuroprotect...

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Bibliographic Details
Main Authors: Jue He, Qian Zu, Chunyan Wen, Qianqian Liu, Pan You, Xinmin Li, Wenqiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Psychiatry
Subjects:
quetiapine
MK-801
schizophrenia
memory
prepulse inhibition deficit
demyelination
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00843/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2020.00843/full

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