HiMMe: using genetic patterns as a proxy for genome assembly reliability assessment

HiMMe: using genetic patterns as a proxy for genome assembly reliability assessment

Abstract Background The information content of genomes plays a crucial role in the existence and proper development of living organisms. Thus, tremendous effort has been dedicated to developing DNA sequencing technologies that provide a better understanding of the underlying mechanisms of cellular p...

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Bibliographic Details
Main Authors: Jordi Abante, Noushin Ghaffari, Charles D. Johnson, Aniruddha Datta
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Genomics
Subjects:
Genome assemblies
de novo assemblies
Sequence analysis
Hidden Markov models
Markov chains
Stochastic processes
Online Access:http://link.springer.com/article/10.1186/s12864-017-3965-2

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http://link.springer.com/article/10.1186/s12864-017-3965-2

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