Characterization of UVA-Induced Alterations to Transfer RNA Sequences

Ultraviolet radiation (UVR) adversely affects the integrity of DNA, RNA, and their nucleoside modifications. By employing liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based RNA modification mapping approaches, we identified the transfer RNA (tRNA) regions most vulnerable to photooxidati...

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Bibliographic Details
Main Authors: Congliang Sun, Patrick A. Limbach, Balasubrahmanyam Addepalli
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomolecules
Subjects:
UVR
Online Access:https://www.mdpi.com/2218-273X/10/11/1527