The immunodominant T cell epitopes of the mycolyl-transferases of the antigen 85 complex of M. tuberculosis.
The Ag85 complex is a 30-32 kD family of three proteins (Ag85A, Ag85B and Ag85C), which all three possess enzymatic mycolyl-transferase activity involved in the coupling of mycolic acids to the arabinogalactan of the cell wall and in the biogenesis of cord factor. By virtue of their strong potential...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-07-01
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| Series: | Frontiers in Immunology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00321/full |