Anticonvulsant Profiles of Certain New 6-Aryl-9-substituted-6,9-diazaspiro-[4.5]decane-8,10-diones and 1-Aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones

Anticonvulsant Profiles of Certain New 6-Aryl-9-substituted-6,9-diazaspiro-[4.5]decane-8,10-diones and 1-Aryl-4-substituted-1,4-diazaspiro[5.5]undecane-3,5-diones

Synthesis and anticonvulsant potential of certain new 6-aryl-9-substituted-6,9-diazaspiro[4.5]decane-8,10-diones (6a–l) and 1-aryl-4-substituted-1,4-diazaspiro[5.5] undecane-3,5-diones (6m–x) are reported. The intermediates 1-[(aryl)(cyanomethyl)amino] cycloalkanecarboxamides (3a–f) were prepared vi...

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Bibliographic Details
Main Authors: Mohamed N. Aboul-Enein, Aida A. El-Azzouny, Mohamed I. Attia, Yousreya A. Maklad, Mona E. Aboutabl, Fatma Ragab, Walaa H. A. Abd El-Hamid
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
cycloalkanones
Strecker synthesis
alkylation
spiro compounds
tetrazole
anticonvulsant
Online Access:http://www.mdpi.com/1422-0067/15/9/16911

Internet

http://www.mdpi.com/1422-0067/15/9/16911

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