Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5.

The mechanisms underlying human cytomegalovirus (HCMV) latency remain incompletely understood. Here, we showed that a HCMV-encoded miRNA, miR-UL148D, robustly accumulates during late stages of experimental latent HCMV infection in host cells and promotes HCMV latency by modulating the immediate earl...

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Bibliographic Details
Main Authors: Chaoyun Pan, Dihan Zhu, Yan Wang, Limin Li, Donghai Li, Fenyong Liu, Chen-Yu Zhang, Ke Zen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5100954?pdf=render