Effective Topical Treatment of Subcutaneous Murine B16F10-Nex2 Melanoma By the Antimicrobial Peptide Gomesin

Effective Topical Treatment of Subcutaneous Murine B16F10-Nex2 Melanoma By the Antimicrobial Peptide Gomesin

Gomesin is a potent antimicrobial peptide (AMP) isolated from hemocytes of the spider Acanthoscurria gomesiana. The present study aimed at determining whether gomesin exerted antitumor activity in vitro and in vivo. Topical treatment of subcutaneous murine melanoma with gomesin incorporated in a cr...

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Bibliographic Details
Main Authors: Elaine G. Rodrigues, Andrey S.S. Dobroff, Clarissa F. Cavarsan, Thaysa Paschoalin, Leonardo Nimrichter, Renato A. Mortara, Edson Lucas Santos, Marcos A. Fázio, Antonio Miranda, Sirlei Daffre, Luiz R. Travassos
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608801121

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http://www.sciencedirect.com/science/article/pii/S1476558608801121

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