Potential Involvement of Adiponectin Signaling in Regulating Physical Exercise-Elicited Hippocampal Neurogenesis and Dendritic Morphology in Stressed Mice

Potential Involvement of Adiponectin Signaling in Regulating Physical Exercise-Elicited Hippocampal Neurogenesis and Dendritic Morphology in Stressed Mice

Adiponectin, a cytokine secreted by mature adipocytes, proves to be neuroprotective. We have previously reported that running triggers adiponectin up-regulation which subsequently promotes generation of hippocampal neurons and thereby alleviates depression-like behaviors in non-stressed mice. Howeve...

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Bibliographic Details
Main Authors: Pingjie Wang, Yiyao Liang, Kai Chen, Suk-Yu Yau, Xin Sun, Kenneth King-Yip Cheng, Aimin Xu, Kwok-Fai So, Ang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
depression
voluntary exercise
adiponectin
dentate gyrus
hippocampal neurogenesis
dendritic plasticity
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00189/full

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https://www.frontiersin.org/article/10.3389/fncel.2020.00189/full

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