Detection of point mutations by non-isotopic single strand conformation polymorphism

We have developed a procedure for nonradioactive single strand conformation polymorphism analysis and applied it to the detection of point mutations in the human tumor suppressor gene p53. The protocol does not require any particular facilities or equipment, such as radioactive handling, large gel u...

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Bibliographic Details
Main Authors: N.A. Pinheiro, R.P. Moura, E. Monteiro, L.L. Villa
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
PCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100008