Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond

Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond

Current approaches have failed to yield success in the translation of neuroprotective therapies from the pre-clinical to the clinical arena for traumatic brain injury (TBI). Numerous explanations have been put forth in both the pre-clinical and clinical arenas. Operation Brain Trauma Therapy (OBTT),...

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Bibliographic Details
Main Authors: Patrick M. Kochanek, C. Edward Dixon, Stefania Mondello, Kevin K. K. Wang, Audrey Lafrenaye, Helen M. Bramlett, W. Dalton Dietrich, Ronald L. Hayes, Deborah A. Shear, Janice S. Gilsdorf, Michael Catania, Samuel M. Poloyac, Philip E. Empey, Travis C. Jackson, John T. Povlishock
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
biomarker
pre-clinical consortium
neuroprotection
drug screening
reproducibility
theranostic
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00640/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00640/full

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