Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia

Even though clonally originated from a single cell, acute leukemia loses its homogeneity soon and presents at clinical diagnosis as a hierarchy of cells endowed with different functions, of which only a minority possesses the ability to recapitulate the disease. Due to their analogy to hematopoietic...

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Bibliographic Details
Main Authors: Federico Mosna, Michele Gottardi
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/7625827