Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis

Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis

Brown adipose tissue (BAT) is composed of thermogenic cells that convert chemical energy into heat to maintain a constant body temperature and counteract metabolic disease. The metabolic adaptations required for thermogenesis are not fully understood. Here, we explore how steady state levels of meta...

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Bibliographic Details
Main Authors: Vanja Panic, Stephanie Pearson, James Banks, Trevor S Tippetts, Jesse N Velasco-Silva, Sanghoon Lee, Judith Simcox, Gisela Geoghegan, Claire L Bensard, Tyler van Ry, Will L Holland, Scott A Summers, James Cox, Gregory S Ducker, Jared Rutter, Claudio J Villanueva
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
pyruvate
mitochondria
thermogenesis
glucose oxidations
glycolysis
ketones
Online Access:https://elifesciences.org/articles/52558

Internet

https://elifesciences.org/articles/52558

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