saeRS and sarA act synergistically to repress protease production and promote biofilm formation in Staphylococcus aureus.

Mutation of the staphylococcal accessory regulator (sarA) limits biofilm formation in diverse strains of Staphylococcus aureus, but there are exceptions. One of these is the commonly studied strain Newman. This strain has two defects of potential relevance, the first being mutations that preclude an...

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Bibliographic Details
Main Authors: Lara N Mrak, Agnieszka K Zielinska, Karen E Beenken, Ian N Mrak, Danielle N Atwood, Linda M Griffin, Chia Y Lee, Mark S Smeltzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3369899?pdf=render