Gain-Of-Function E76K-Mutant SHP2 Promotes Cell Proliferation, Metastasis, And Tumor Growth In Glioblastoma Through Activation Of The ERK/CREB Pathway

Gain-Of-Function E76K-Mutant SHP2 Promotes Cell Proliferation, Metastasis, And Tumor Growth In Glioblastoma Through Activation Of The ERK/CREB Pathway

Fan Yang,1,2 Mo Xu,1 Shiqing Wang,1 Le Song,1 Dandan Yu,1 Yao Li,1 Rui Cao,1 Zhang Xiong,1,2 Zhijun Chen,1 Qian Zhang,1 Bing Zhao,2 Siying Wang1 1School of Basic Medical Sciences, Anhui Medical University, Hefei, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliate...

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Bibliographic Details
Main Authors: Yang F, Xu M, Wang S, Song L, Yu D, Li Y, Cao R, Xiong Z, Chen Z, Zhang Q, Zhao B
Format: Article
Language:English
Published: Dove Medical Press 2019-11-01
Series:OncoTargets and Therapy
Subjects:
glioblastoma
e76k mutation
shp2
malignant behavior
erk
creb
cancer
Online Access:https://www.dovepress.com/gain-of-function-e76k-mutant-shp2-promotes-cell-proliferation-metastas-peer-reviewed-article-OTT

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https://www.dovepress.com/gain-of-function-e76k-mutant-shp2-promotes-cell-proliferation-metastas-peer-reviewed-article-OTT

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