Astrocytic Glutamate Transporter 1 (GLT1) Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice

Glutamatergic dysregulation is known to contribute to altered emotional regulation. Astrocytic glutamate transporter 1 (GLT1) is responsible for the majority of glutamate clearance from synapse. However, the role of astrocytic GLT1 in affective processes such as anxiety- and depression-like behavior...

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Bibliographic Details
Main Authors: Yun-Fang Jia, Katheryn Wininger, Ada Man-Choi Ho, Lee Peyton, Matthew Baker, Doo-Sup Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Behavioral Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2020.00057/full