Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses

Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses

Antigen-specific lung-resident memory T cells (TRMs) constitute the first line of defense that mediates rapid protection against respiratory pathogens and inspires novel vaccine designs against infectious pandemic threats, yet effective means of inducing TRMs, particularly via non-viral vectors, rem...

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Bibliographic Details
Main Authors: Pin-Hung Lin, Chieh-Yu Liang, Bing-Yu Yao, Hui-Wen Chen, Ching-Fu Pan, Li-Ling Wu, Yi-Hsuan Lin, Yu-Sung Hsu, Yu-Han Liu, Pei-Jer Chen, Che-Ming Jack Hu, Hung-Chih Yang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
resident memory T cell
nanoshell
T cell vaccine
peptide vaccine
influenza virus
universal influenza vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000504

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http://www.sciencedirect.com/science/article/pii/S2329050121000504

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