Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is required for stable Polycomb-mediated gene repression in Arabidopsis

Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is required for stable Polycomb-mediated gene repression in Arabidopsis

Abstract Background Stable gene repression is essential for normal growth and development. Polycomb repressive complexes 1 and 2 (PRC1&2) are involved in this process by establishing monoubiquitination of histone 2A (H2Aub1) and subsequent trimethylation of lysine 27 of histone 3 (H3K27me3). Pre...

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Bibliographic Details
Main Authors: Lejon E. M. Kralemann, Shujing Liu, Minerva S. Trejo-Arellano, Rafael Muñoz-Viana, Claudia Köhler, Lars Hennig
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Genome Biology
Subjects:
H2AK121ub
H2Aub
H3K27me3
PRC1
PRC2
EMF1
Online Access:http://link.springer.com/article/10.1186/s13059-020-02062-8

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http://link.springer.com/article/10.1186/s13059-020-02062-8

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