Postnatal Involution and Counter-Involution of the Thymus

Thymus involution occurs in all vertebrates. It is thought to impact on immune responses in the aged, and in other clinical circumstances such as bone marrow transplantation. Determinants of thymus growth and size are beginning to be identified. Ectopic expression of factors like cyclin D1 and Myc i...

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Bibliographic Details
Main Authors: Jennifer E. Cowan, Yousuke Takahama, Avinash Bhandoola, Izumi Ohigashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Myc
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00897/full