Who Is Afraid of CRP? Elevated Preoperative CRP Levels Might Attenuate the Increase in Inflammatory Parameters in Response to Lung Cancer Surgery

Who Is Afraid of CRP? Elevated Preoperative CRP Levels Might Attenuate the Increase in Inflammatory Parameters in Response to Lung Cancer Surgery

During surgery, ATP from damaged cells induces the release of interleukin-1β, a potent pro-inflammatory cytokine that contributes to the development of postoperative systemic inflammation, sepsis and multi-organ damage. We recently demonstrated that C-reactive protein (CRP) inhibits the ATP-induced...

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Bibliographic Details
Main Authors: Moritz Mecki Meyer, Leon Brandenburg, Helge Hudel, Alisa Agné, Winfried Padberg, Ali Erdogan, Holger Nef, Anca-Laura Amati, Oliver Dörr, Biruta Witte, Veronika Grau
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Clinical Medicine
Subjects:
atorvastatin
C-reactive protein
fever
gender
inflammatory complications
interleukin-1β
Online Access:https://www.mdpi.com/2077-0383/9/10/3340

Internet

https://www.mdpi.com/2077-0383/9/10/3340

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