Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation

Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation

Background: Autophagy plays a significant role in myocardial ischemia reperfusion (IR) injury. Hydrogen sulfide (H2S) has been demonstrated to protect cardiomyocytes against IR injury, while whether it has anti-autophagy effect has not been known. The aim of this study was to investigate whether H2S...

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Bibliographic Details
Main Authors: Jian Xiao, Xiaoyan Zhu, Bo Kang, Jibin Xu, Lihui Wu, Jiang Hong, Yufeng Zhang, Xin Ni, Zhinong Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Autophagy
mTOR
H2S
Hypoxia-reoxygenation
Cardiomyocyte
Online Access:http://www.karger.com/Article/FullText/438597

Internet

http://www.karger.com/Article/FullText/438597

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