Organoid-Transplant Model Systems to Study the Effects of Obesity on the Pancreatic Carcinogenesis in vivo

Organoid-Transplant Model Systems to Study the Effects of Obesity on the Pancreatic Carcinogenesis in vivo

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related mortality among adults in developed countries. The discovery of the most common genetic alterations as well as the development of organoid models of pancreatic cancer have provided insight into the fundamental pathw...

Full description

Bibliographic Details
Main Authors: Francesca Lupo, Geny Piro, Lorena Torroni, Pietro Delfino, Rosalinda Trovato, Borislav Rusev, Alessandra Fiore, Dea Filippini, Francesco De Sanctis, Marcello Manfredi, Emilio Marengo, Rita Teresa Lawlor, Maurizio Martini, Giampaolo Tortora, Stefano Ugel, Vincenzo Corbo, Davide Melisi, Carmine Carbone
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
obesity
organoid models
pancreatic cancer
carcinogenesis
adipokines
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00308/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00308/full

Similar Items