Downregulation of caveolin-1 enhances fusion of human BeWo choriocarcinoma cells.

Fusion of placental villous cytotrophoblasts with the overlying syncytiotrophoblast is essential for the maintenance of successful pregnancy, and disturbances in this process have been implicated in pathological conditions such as pre-eclampsia and intra-uterine growth retardation. Caveolin-1 has be...

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Bibliographic Details
Main Authors: Gavin P Collett, Elizabeth A Linton, Christopher W G Redman, Ian L Sargent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2865536?pdf=render