All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells

All-trans retinoic acid reduces cancer stem cell-like cell-mediated resistance to gefitinib in NSCLC adenocarcinoma cells

Abstract Background The enrichment of cancer stem cell-like cells (CSCs) has been considered to be responsible for tumor progression after an initial response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in patients with non-small cell lung adenocarcinoma (NSCLC/...

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Bibliographic Details
Main Authors: Wenxiu Yao, Liyang Wang, Huan Huang, Xin Li, Pinjia Wang, Kun Mi, Jia Cheng, Huifen Liu, Cuirong Gu, Lingxiao Huang, Jianming Huang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
All-trans retinoic acid
ALDH1A1
CD44
EGFR tyrosine kinase inhibitors
Non-small cell lung adenocarcinoma
Online Access:http://link.springer.com/article/10.1186/s12885-020-06818-0

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http://link.springer.com/article/10.1186/s12885-020-06818-0

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