Early administration of empagliflozin preserved heart function in cardiorenal syndrome in rat

Early administration of empagliflozin preserved heart function in cardiorenal syndrome in rat

This study tested the hypothesis that early administration of empagliflozin (Empa), an inhibitor of glucose recycling in renal tubules, could preserve heart function in cardiorenal syndrome (CRS) in rat. Chronic kidney disease (CKD) was caused by 5/6 subtotal nephrectomy and dilated cardiomyopathy (...

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Bibliographic Details
Main Authors: Chih-Chao Yang, Yen-Ta Chen, Christopher Glenn Wallace, Kuan-Hung Chen, Ben-Chung Cheng, Pei-Hsun Sung, Yi-Chen Li, Sheung-Fat Ko, Hsueh-Wen Chang, Hon-Kan Yip
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Empagliflozin
Cardiorenal syndrome
Heart function
Inflammation
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218344184

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218344184

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