Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Oct4 upregulates osteopontin via Egr1 and is associated with poor outcome in human lung cancer

Abstract Background Roles of cancer stem cells and early growth response gene 1 (Egr1) in carcinogenesis have been extensively studied in lung cancer. However, the role of Egr1 in the metastasis of lung cancer remains undetermined, especially in regard to stem cell-related pathways. Methods Egr1, os...

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Bibliographic Details
Main Authors: Yin-Hsun Feng, Yu-Chu Su, Shuo-Fu Lin, Pey-Ru Lin, Chao-Liang Wu, Chao-Ling Tung, Chien-Feng Li, Gia-Shing Shieh, Ai-Li Shiau
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Oct4
Egr1
Osteopontin
Lung cancer
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12885-019-6014-5

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http://link.springer.com/article/10.1186/s12885-019-6014-5

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