High and low doses of ionizing radiation induce different secretome profiles in a human skin model.

It is postulated that secreted soluble factors are important contributors of bystander effect and adaptive responses observed in low dose ionizing radiation. Using multidimensional liquid chromatography-mass spectrometry based proteomics, we quantified the changes of skin tissue secretome--the prote...

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Bibliographic Details
Main Authors: Qibin Zhang, Melissa Matzke, Athena A Schepmoes, Ronald J Moore, Bobbie-Jo Webb-Robertson, Zeping Hu, Matthew E Monroe, Wei-Jun Qian, Richard D Smith, William F Morgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958549?pdf=render