Importance of Fc-mediated functions of anti-HIV-1 broadly neutralizing antibodies

Abstract Anti-HIV-1 broadly neutralizing antibodies (BnAbs) exhibit an impressive capacity to protect against chimeric SIV-HIV (SHIV) challenges in macaques and potently reduce viremia in both SHIV-infected macaques and HIV-1-infected humans. There is a body of evidence suggesting Fc-mediated functi...

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Bibliographic Details
Main Authors: Matthew S. Parsons, Amy W. Chung, Stephen J. Kent
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-018-0438-x