Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice

Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice

Abstract Background Recent studies indicated that circulatory factors in blood plasma from young animals can reactivate neurogenesis, restore synaptic plasticity, and improve cognitive function in aged animals. Here, we investigated if young plasma could have a possible therapeutic effect for treatm...

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Bibliographic Details
Main Authors: Ying Zhao, Ran Qian, Jin Zhang, Fei Liu, Khalid Iqbal, Chun-Ling Dai, Cheng-Xin Gong
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Cognitive function
Young blood plasma
Tau
Aβ
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s13195-020-00639-w

Internet

http://link.springer.com/article/10.1186/s13195-020-00639-w

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