Role of renal function in risk assessment of target non-attainment after standard dosing of meropenem in critically ill patients: a prospective observational study

Role of renal function in risk assessment of target non-attainment after standard dosing of meropenem in critically ill patients: a prospective observational study

Abstract Background Severe bacterial infections remain a major challenge in intensive care units because of their high prevalence and mortality. Adequate antibiotic exposure has been associated with clinical success in critically ill patients. The objective of this study was to investigate the targe...

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Bibliographic Details
Main Authors: Lisa Ehmann, Michael Zoller, Iris K. Minichmayr, Christina Scharf, Barbara Maier, Maximilian V. Schmitt, Niklas Hartung, Wilhelm Huisinga, Michael Vogeser, Lorenz Frey, Johannes Zander, Charlotte Kloft
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Critical Care
Subjects:
β-Lactam
Intensive care
Pharmacokinetics/Pharmacodynamics
Target attainment
Renal function
Risk assessment tool
Online Access:http://link.springer.com/article/10.1186/s13054-017-1829-4

Internet

http://link.springer.com/article/10.1186/s13054-017-1829-4

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