Stochasticity in protein levels drives colinearity of gene order in metabolic operons of Escherichia coli.
In bacterial genomes, gene order is not random. This is most evident when looking at operons, these often encoding enzymes involved in the same metabolic pathway or proteins from the same complex. Is gene order within operons nonrandom, however, and if so why? We examine this issue using metabolic o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-05-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC2684527?pdf=render |