Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation–Processing Aspects and Challenges

Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation–Processing Aspects and Challenges

Drug nanoparticles embedded in a dispersant matrix as a secondary phase, i.e., drug-laden nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and bioavailability of poorly water-soluble drugs. Drug nanoparticles are prepared by top-down, bottom-up, or combinative a...

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Bibliographic Details
Main Authors: Anagha Bhakay, Mahbubur Rahman, Rajesh N. Dave, Ecevit Bilgili
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceutics
Subjects:
BCS Class II drugs
drug nanosuspensions
nanocomposites
redispersion
dissolution enhancement
aggregates
formulation
Online Access:http://www.mdpi.com/1999-4923/10/3/86

Internet

http://www.mdpi.com/1999-4923/10/3/86

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