HPV E6 and E7 oncoproteins cooperatively alter the expression of Disc Large 1 polarity protein in epithelial cells

Abstract Background Persistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins. Among the oncogenic activities of E6, the intera...

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Bibliographic Details
Main Authors: María Paula Dizanzo, Federico Marziali, Clarisse Brunet Avalos, Marina Bugnon Valdano, Santiago Leiva, Ana Laura Cavatorta, Daniela Gardiol
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
HPV
Online Access:http://link.springer.com/article/10.1186/s12885-020-06778-5