The RhoA-ROCK pathway in the regulation of T and B cell responses [version 1; referees: 3 approved]

Effective immune responses require the precise regulation of dynamic interactions between hematopoietic and non-hematopoietic cells. The Rho subfamily of GTPases, which includes RhoA, is rapidly activated downstream of a diverse array of biochemical and biomechanical signals, and is emerging as an i...

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Bibliographic Details
Main Authors: Edd Ricker, Luvana Chowdhury, Woelsung Yi, Alessandra B. Pernis
Format: Article
Language:English
Published: F1000 Research Ltd 2016-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-2295/v1