Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells.

Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells.

CD4(+)CD25(+)FOXP3(+) Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in human. Experiments in mice demonstrated that Treg restrict effector T cell (Teff) responses by deprivat...

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Bibliographic Details
Main Authors: Yvonne Vercoulen, Ellen J Wehrens, Nienke H van Teijlingen, Wilco de Jager, Jeffrey M Beekman, Berent J Prakken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2746309?pdf=render

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http://europepmc.org/articles/PMC2746309?pdf=render

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