Tear Film Pharmacokinetics and Systemic Absorption Following Topical Administration of 1% Prednisolone Acetate Ophthalmic Suspension in Dogs

The study aimed to determine the tear film pharmacokinetics following topical administration of 1% prednisolone acetate—assessing whether two drops would provide a superior kinetic profile compared to one drop—and to determine the fraction of an eye drop that reaches the systemic circulation in dogs...

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Bibliographic Details
Main Authors: Lionel Sebbag, Nicolette S. Kirner, Larry W. Wulf, Jonathan P. Mochel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.571350/full