SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung

SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung

Extensive fibrin deposition in the lungs and altered levels of circulating blood coagulation proteins in COVID-19 patients imply local derangement of pathways that limit fibrin formation and/or promote its clearance. We examined transcriptional profiles of bronchoalveolar lavage fluid (BALF) samples...

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Bibliographic Details
Main Authors: Alan E Mast, Alisa S Wolberg, David Gailani, Michael R Garvin, Christiane Alvarez, J Izaak Miller, Bruce Aronow, Daniel Jacobson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
COVID-19
coagulation
fibrinolysis
bronchoalvelolar
SARS-CoV-2
Online Access:https://elifesciences.org/articles/64330

Internet

https://elifesciences.org/articles/64330

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