Interleukin-12 gene adjuvant increases the immunogenicity of virus-like particles of human papillomavirus type 16 regional variant strain

Objectives: To analyze the immunogenicity of virus-like particles (VLP) of human papillomavirus type 16 (HPV16) isolated in East China and the adjuvant potential of interleukin-12 (IL-12). Methods: The variant HPV16 L1VLP expressed in sf9 insect cells were purified with cesium chloride gradient cent...

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Bibliographic Details
Main Authors: Lanlan Wei, Ming Chu, Qingmeng Zhang, Yan Wang, Qinglong Shang, Yunyan Zhang, Guangmei Zhang
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867013002316