Combination of ester biosynthesis and ω-oxidation for production of mono-ethyl dicarboxylic acids and di-ethyl esters in a whole-cell biocatalytic setup with Escherichia coli

Combination of ester biosynthesis and ω-oxidation for production of mono-ethyl dicarboxylic acids and di-ethyl esters in a whole-cell biocatalytic setup with Escherichia coli

Abstract Background Medium chain length (C6–C12) α,ω-dicarboxylic acids (DCAs) and corresponding esters are important building blocks for the polymer industry. For DCAs of 12 carbon atoms and longer, a sustainable process based on monooxygenase catalyzed ω-oxidation of fatty-acids has been realized....

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Bibliographic Details
Main Authors: Youri M. van Nuland, Gerrit Eggink, Ruud A. Weusthuis
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Microbial Cell Factories
Subjects:
Whole-cell biocatalysis
α,ω-dicarboxylic acids
Adipic acid
Esters
Monooxygenases
Online Access:http://link.springer.com/article/10.1186/s12934-017-0803-9

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http://link.springer.com/article/10.1186/s12934-017-0803-9

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