Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration

<p>Abstract</p> <p>Background</p> <p>Aberrations in DNA methylation patterns promote changes in gene expression patterns and are invariably associated with neoplasia. DNA methylation is carried out and maintained by several DNA methyltransferases (DNMTs) among which DNM...

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Bibliographic Details
Main Authors: Qazi Romena, Qureshi Sohail A, Yaqinuddin Ahmed, Abbas Farhat
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/8/1/13