Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration
<p>Abstract</p> <p>Background</p> <p>Aberrations in DNA methylation patterns promote changes in gene expression patterns and are invariably associated with neoplasia. DNA methylation is carried out and maintained by several DNA methyltransferases (DNMTs) among which DNM...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-09-01
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Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/8/1/13 |