How can cells sense the elasticity of a substrate? An analysis using a cell tensegrity model

How can cells sense the elasticity of a substrate? An analysis using a cell tensegrity model

A eukaryotic cell attaches and spreads on substrates, whether it is the extracellular matrix naturally produced by the cell itself, or artificial materials, such as tissue-engineered scaffolds. Attachment and spreading require the cell to apply forces in the nN range to the substrate via adhesion si...

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Bibliographic Details
Main Authors: G De Santis, AB Lennon, F Boschetti, B Verhegghe, P Verdonck, PJ Prendergast
Format: Article
Language:English
Published: AO Research Institute Davos 2011-10-01
Series:European Cells & Materials
Subjects:
Biophysical model
tensegrity
matrix elasticity
Finite Element Method
analytical model
mesenchymal stem cells
Online Access:http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a16.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a16.pdf

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