Bioinspired Heparin Nanosponge Prepared by Photo-crosslinking for Controlled Release of Growth Factors

Abstract Growth factors have great therapeutic potential for various disease therapy and tissue engineering applications. However, their clinical efficacy is hampered by low bioavailability, rapid degradation in vivo and non-specific biodistribution. Nanoparticle based delivery systems are being eva...

Full description

Bibliographic Details
Main Authors: Won Il Choi, Abhishek Sahu, Cristian Vilos, Nazila Kamaly, Seong-Min Jo, Jin Hyung Lee, Giyoong Tae
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-14040-5