Reprogrammed transcriptome in rhesus-bovine interspecies somatic cell nuclear transfer embryos.

Global activation of the embryonic genome (EGA), one of the most critical steps in early mammalian embryo development, is recognized as the time when interspecies somatic cell nuclear transfer (iSCNT) embryos fail to thrive.In this study, we analyzed the EGA-related transcriptome of rhesus-bovine iS...

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Bibliographic Details
Main Authors: Kai Wang, Hasan H Otu, Ying Chen, Young Lee, Keith Latham, Jose B Cibelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143123?pdf=render